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Microcirculatory and clinical and morphological features of the oral mucosa in patients with atherosclerosis and periodontal diseases: a systematic review Microcirculation disorders are considered as one of the key pathogenetic links of inflammatory periodontal diseases and systemic cardiovascular pathology. In recent years, atherosclerosis has increasingly been interpreted as a chronic inflammat…

Biomimetic materials and minimally invasive techniques in contemporary prosthodontics: innovative solutions for preserving natural tooth structure Contemporary prosthodontics is shifting from retention-based full-coverage designs to biomimetic, tissue-sparing solutions that prioritize maximal enamel preservation, judicious dentin management, and sustained function and aesthetics. Aim. To synthesi…

Assessment of the organization of medical rehabilitation of children with oncological and hematological diseases in the subjects of the Russian Federation Background. Medical rehabilitation of children who have suffered from oncological and hematological diseases is a critically important stage for improving the long-term quality of life. However, in the regions of the Russian Federation, access …

Study of antibacterial activity of zinc oxide coated textiles Background. Nowadays, due to the widespread of antibiotic-resistant bacteria, in addition to traditional methods of treating surface infections using mechanical cleaning, antiseptics and antibiotics, variants of dressings with antibacterial coating with inorganic and hybrid nanoparticles are being investigated and tested. The developme…

Assessing the role of interferons in congenital and acquired interferonopathies: a review Impaired interferon (IFN) production plays a key role in the pathogenesis of a wide range of autoimmune diseases (AIDs), such as systemic lupus erythematosus (SLE), multiple sclerosis (MS), dermatomyositis, and others. This review examines both the physiological functions of IFNs under normal conditions (ant…

Step-up strategy for the treatment of infected pseudocysts and infected walled-off necrosis: a prospective observational study Background. Infected pseudocysts and infected walled-off necrosis (WON) are severe complications of acute pancreatitis associated with high mortality rates (up to 35%) following open surgery. The use of lumen-apposing metal stents (LAMS) enables minimally invasive endosco…

Oncogastroenterology — a new direction in the development of multidisciplinary clinical medicine Due to the high prevalence and increasing mortality from cancer, including gastrointestinal tumors, numerous challenges arise in the diagnosis, treatment, and management of patients, often requiring the intervention of doctors in related specialties. One such pressing issue is multidisciplinary collab…

To the 90th anniversary of Academician of the Russian Academy of Sciences Igor Ivanovich Zatevakhin On the 90th Anniversary of Academician of the Russian Academy of Sciences Igor Ivanovich On February 20, 2026, the 90th anniversary was celebrated by Igor Ivanovich Zatevakhin, an outstanding scientist, a world-renowned surgeon, a prominent public figure, a talented teacher, an Honored Scientist of…

Leprosy recurrences in the Astrakhan region (1951–2020): a long-term analysis of incidence, risk factors, and treatment outcomes Background. Despite significant progress in controlling leprosy incidence, the problem of relapses remains relevant, especially in endemic regions. Analysis of long-term dynamics of relapses and factors influencing their development is necessary to optimize treatment ta…

Association of polymorphic markers Arg753Gln in the <i>TLR2</i> Gene, T-1237C and G2848A in the <i>TLR9</i> Gene with the risk of developing primary adrenal insufficiency in individuals living in the Moscow Region of the Russian Federation Background. Primary adrenal insufficiency (PAI) is an endocrine disorder caused by the gradual destruction of all three layers of the adrenal cortex and charac…